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Oxytrol (OXYBUTYNIN) is a transdermal system, designed to deliver oxybutynin continuously and consistently over a 3- to 4-day interval after application to intact skin. Oxytrol is indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency.
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Oxybutynin reduces muscle spasms of the bladder and urinary tract.
Oxytrol is used to treat symptoms of overactive bladder, such as frequent or urgent urination, incontinence (urine leakage), and increased nighttime urination.
Oxytrol may also be used for purposes other than those listed in this medication guide.
Before using
Do not use Oxytrol if you are allergic to oxybutynin, or if you have:
• untreated or uncontrolled glaucoma;
• a blockage in your digestive tract (stomach or intestines); or
• if you have decreased urination or are unable to urinate.
Before using Oxytrol, tell your doctor if you are allergic to any drugs, or if you have:
• glaucoma;
• liver disease;
• kidney disease;
• myasthenia gravis;
• an enlarged prostate;
• an intestinal disorder, such as ulcerative colitis; or
• a stomach disorder such as gastroesophageal reflux disease (GERD) or slow digestion.
If you have any of these conditions, you may not be able to use Oxytrol, or you may need a dosage adjustment or special tests during treatment.
Directions
Use this medication exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor. Follow the instructions on your prescription label.
Oxytrol comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.
Cautions
Do not use Oxytrol if you are allergic to oxybutynin, or if you have uncontrolled glaucoma, a blockage in your stomach or intestines, or if you are unable to urinate. Oxybutynin can cause blurred vision, drowsiness, or dizziness. Be careful if you drive or do anything that requires you to be alert and able to see clearly. Avoid drinking alcohol. It can increase some of the side effects of oxybutynin.
Avoid becoming overheated or dehydrated during exercise and in hot weather. Drink plenty of fluids to keep yourself hydrated while you are using oxybutynin.
Do not expose the Oxytrol patch to sunlight. It should be worn under clothing.
Possible side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Oxytrol and call your doctor at once if you have any of these serious side effects:
• fever with hot, dry skin;
• uneven heart rate;
• pain, burning, or other difficulty when urinating; or
• severe itching, burning, or blistering that does not clear up within several hours after removing the skin patch.
Continue using Oxytrol and talk to your doctor if you have any of these less serious side effects:
• mild skin itching, burning, redness, or discoloration where a patch was worn;
• dizziness, drowsiness, weakness;
• blurred vision;
• dry mouth;
• warmth, tingling, or redness under your skin;
• nausea, vomiting, stomach pain;
• constipation or diarrhea;
• dry eyes;
• stuffy nose;
• back pain;
• feeling restless; or
• sleep problems (insomnia).
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
If you take too much
Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of an Oxytrol overdose may include restlessness, tingly feeling, fever, uneven heart rate, vomiting, and urinating less than usual or not at all.
Additional information
Oxybutynin can cause blurred vision, drowsiness, or dizziness. Be careful if you drive or do anything that requires you to be alert and able to see clearly. Avoid drinking alcohol. It can increase some of the side effects of oxybutynin.
Avoid becoming overheated or dehydrated during exercise and in hot weather. Drink plenty of fluids to keep yourself hydrated while you are using Oxytrol.
Do not expose the Oxytrol transdermal patch to sunlight. It should be worn under clothing.
Avoid using other medicines that make you sleepy (such as cold medicine, pain medication, muscle relaxers, and medicine for seizures, depression or anxiety). They can add to sleepiness caused by Oxytrol.
Drug interactions
Before using Oxytrol, tell your doctor if you are using any of the following drugs:
• atropine (Donnatal, and others);
• belladonna;
• clidinium (Quarzan);
• dicyclomine (Bentyl);
• glycopyrrolate (Robinul);
• hyoscyamine (Anaspaz, Cystospaz, Levsin, and others);
• mepenzolate (Cantil);
• methantheline (Provocholine);
• methscopolamine (Pamine);
• propantheline (Pro-Banthine);
• scopolamine (Transderm-Scop);
• antibiotics such as clarithromycin (Biaxin), erythromycin (E-Mycin, E.E.S., Ery-Tab, Erythrocin), itraconazole (Sporanox), or ketoconazole (Nizoral).
If you are using any of these drugs, you may not be able to use Oxytrol, or you may need dosage adjustments or special tests during treatment.
There may be other drugs not listed that can affect Oxytrol. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
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